My husband has psoriatic arthritis and was on methotrexate for several years but he stopped taking that due to the side effects but carried on taking anti-inflammatories and painkillers. He has been using the Arc for about 10 weeks, every day for 6 weeks and more recently lowered it to a few times a week. He hasn’t taken any anti-inflammatories at all and he has had maybe one painkiller a week whereas he was taken both nearly everyday, so great improvement.